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I see the "ini" and "json" actions in CleanerML documentation.
Are those applicable only to those exact file extensions?

What about cleaning sections from XML files, where the file contains custom settings, plus search term history, etc? Is there any way to do this?

I looked at a couple of dozen cleaners. They involve deleting entire files, or using defined actions.

For instance, in Linux the ~/.gnome-commander/Gnome-Commander.xml file holds lots of custom settings, but also search terms, "replace with" data, and batch rename data.